Copeptin: Overcome the Limitation of Vasopressin (AVP/ADH) Measurement

Arginine vasopressin (AVP), also called antidiuretic hormone (ADH) is one of the key hormones in the human body. AVP has important physiological functions, including vascular tonus, the homeostasis of fluid balance and regulation of the endocrine stress response.^Ref-1 But due to technical limitations of vasopressin assays, vasopressin concentrations were rarely measured in the past.

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Advantages of Copeptin measurement

Stable

Extremely high stability ex vivo
Ex vivo Copeptin stability (<20% loss of analyte) has been shown even for at least 7 days at room temperature. ^Ref-2

Reliable

Not significantly bound to platelets
Results you can trust; AVP in contrast is bound to platelets leading to falsely elevated or varying measurements of free plasma AVP. ^Ref-2

Easy to measure

Sensitive Automated sandwich-immunoassay
B·R·A·H·M·S Copeptin proAVP KRYPTOR is available on KRYPTOR Compact PLUS, a fully automated bench-top analyzer with easy and continuous sample loading backed by the Nobel Prize-winning TRACE technology.

Precise

Correlates better with serum osmolality than Vasopressin itself
Copeptin helps to better evaluate response to osmotic and haemodynamic changes. ^Ref-3

Convenient

Reduced physical and psychological stress for patients
The ease and speed of B·R·A·H·M·S Copeptin proAVP KRYPTOR assay improves the diagnosis of AVP-dependent fluid disorders, for a better patients care. ^{Ref-4, Ref-5, Ref-6}

Quick

Fast turnaround time
Results are available in less than 30 minutes.