Optimized lab workflow with self-determining dilution factor (SDDF)

Watch how self-determining dilution factor (SDDF) is calculating dilution factor and executes the dilution with no user interference.

Improved management of out of range (OOR) samples

Fast, accurate and reliable lab test results enable confident clinical decisions. Delays in reporting results can often have detrimental impact on both patient and healthcare provider, and as such, turnaround time is a key performance indicator of well-functioning laboratories. A frequent challenge to report results quickly, is the accurate measurement and processing of an out of range sample. By using BꞏRꞏAꞏHꞏMꞏS KRYPTOR Analyzers, which utilize Nobel Prize winning TRACE technology, it is now possible to eliminate unnecessary processing steps in out of range sample management and optimize turnaround time.

Benefits of Self-determining dilution factor

Benefits of Self-determining dilution factor are

  • Reduce hands-on time
  • Enhance turnaround time
  • Save cost and wastage
  • Avoid dilution errors
  • Minimize hook effect and enhance accuracy

The challenge in detail

Processing an out of range sample would typically require the following steps:

Disadvantages of the above processing steps are

  • An increased turnaround time
  • Delayed patient results
  • Increased error rates

Reducing turnaround time with BꞏRꞏAꞏHꞏMꞏS KRYPTOR Analyzers

BꞏRꞏAꞏHꞏMꞏS KRYPTOR Analyzers are the only immuno analyzers in the market that fully automated all necessary steps which are required for a dilution.

Using Nobel Prize winning TRACE (Time Resolved Amplified Cryptate Emission) technology, BꞏRꞏAꞏHꞏMꞏS KRYPTOR Analyzers are able to detect the OOR samples within few minutes into the incubation period and carry out the dilution without any user intervention. This unique feature which optimizes laboratory workflow is named “Self-determining dilution factor” (SDDF)

How does Self-determining dilution factor work?

The incubation period in B·R·A·H·M·S KRYPTOR Analyzers is divided in two phases.

  1. Detection phase
  2. Counting phase.

Incubation starts when the conjugates and sample are dispensed into a well, then the detection phase begins. During this phase by using TRACE, the kinetics of bound & unbound signal will be calculated and precisely predict if the sample concentration will be out of range at the end of incubation period. If sample concentration is predicted to be out of range, the self-determining dilution factor will determine the correct dilution factor autonomously and execute the dilution with no user intervention. Normally it takes BꞏRꞏAꞏHꞏMꞏS KRYPTOR Analyzers only one attempt to identify and perform the dilution with correct dilution factor.

Once the sample concentration is in the direct measuring range, counting phase will begin. At the end of counting phase, measurement is completed, and result will be directly delivered to the user.